Baxter Osmitrol 10% IV Mannitol Infusion 1000ml

Hypertonic: Mannitol 549 mmol/L

Indications: Osmitrol Intravenous Infusion (Mannitol Intravenous Infusion, BP), can be used in:

• The promotion of diuresis, in the prevention and/or treatment of the oliguric phase of acute renal failure, before irreversible renal failure becomes established.
• The reduction of elevated intraocular pressure when the pressure cannot be lowered by other means;
• The reduction of intracranial pressure and treatment of cerebral oedema by reducing brain mass and;
• Promoting the urinary excretion of toxic substances.

Contraindications: Osmitrol Intravenous Infusion (Mannitol BP) is contraindicated in patients with:

• Hypersensitivity to Mannitol
• Pre-existing plasma hyperosmolarity
• Severe heart failure
• Disturbance of the blood-brain barrier
• Well-established anuria due to severe renal disease
• No response to the test dose
• Severe pulmonary congestion or frank pulmonary oedema
• Active intracranial bleeding except during craniotomy
• Severe dehydration
• Progressive renal damage or dysfunction after institution of Mannitol therapy, including increasing oliguria and azotemia, and
• Progressive heart failure or pulmonary congestion after institution of Mannitol therapy

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